The cafeteria scene where Peter catches Mary Jane and her lunch uses no CGI, just adhesive on Tobey Maguire's hand—and 156 takes. (Source)

Director Sam Raimi auditioned several spiders for the role of the arachnid that delivers the life-changing bite to Peter. The spider who snagged the role, a brown Steatoda grossa, was then hand-painted with red and blue accents. (Source)

Want to get buff like Tobey Maguire did to play Spidey? All you need to do is eat four-to-six protein-filled meals a day and exercise, lift weights, and practice martial arts six days a week for five months straight. (Source)

Fellow Marvel superhero Wolverine was originally slated to make a cameo in Spider-Man, but Columbia Pictures couldn't get access to Hugh Jackman's costume from 20th Century Fox. (Source)